Table 1 Demographics for the subjects donating bronchoalveolar lavage samples (COSMIC cohort)
Healthy nonsmokersSmokers without COPDSmokers with COPD
Subjects (n)374033
Sex (female/male)18/1920/2016/17
Age (years)60 (45–65)52.5 (44–65)61 (47–66)
FEV1% Pred119 (89–147)108.8 (91–140)80 (51–97)
FEV1/FVC (%)81 (70–93)78 (71–88)62 (43–75)
Smoking history033.5 (15–66)38 (17–62)
Current smokers04023/33
Ci/day for the last 6 months017 (10–40)15 (0–25)
CB (no/yes)030/1025/8
ICS000
β antagonists002
Anticholinergic002
  • Data shown represent median and range. Abbreviations: CB, chronic bronchitis; Ci, cigarette; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ICS, inhaled corticosteroid.