Table 2 Demographics for the subjects donating BW samples (COSMIC cohort)
Healthy nonsmokersSmokers without COPDSmokers with COPD
Subjects (n)343333
Sex (female/male)17/1716/1716/17
Age (years)60 (46–65)53 (44–65)62 (47–66)
FEV1% Pred120 (92–141)106 (91–130)81.5 (51–97)
FEV1/FVC (%)82 (71–91)78 (71–88)62.5 (43–69)
Smoking history034 (15–84)40 (17–51)
Current smokers03322
Ci/day for the last 6 months017 (10–40)11 (0– 25)
CB (no/yes)024/925/8
ICS000
β antagonists003
Anticholinergic002
  • Data shown represent median and range. Abbreviations: CB, chronic bronchitis; Ci, cigarette; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ICS, inhaled corticosteroid.