Table 1 Effects of CCR2 deficiency on apoE−/− mice infused with either saline or AngII

Values are presented as means±S.E.M. *P<0.05 and †P<0.001 for comparisons of AngII and saline infusion within genotypes; ‡P<0.001 for comparisons of AngII infusion between genotypes.

InfusionGenotypenBody weight (g)Serum cholesterol (mg/dl)Blood pressure (mmHg)
SalineCCR2+/+928.5±0.5703±18120±3
CCR2−/−928.5±0.6688±35128±4
AngIICCR2+/+1627.4±0.5656±24142±4*
CCR2−/−1928.1±0.8820±20†‡142±5*