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Clinical Science Young Investigator Award winner

Justin Davies

Justin Davies graduated from Imperial College School of Medicine in 2000. Since then he has worked at St Mary’s Hospital and Bart’s and the London NHS Trust. In 2005 he was awarded a British Heart Foundation Junior Research Fellowship to undertake a PhD with Dr Jamil Mayet and Professor Alun Hughes at the International Centre of Circulatory Health.

His main research interests are the study of arterial haemodynamics in the coronary arteries and the aorta using wave intensity analysis - a new analytical technique. He has applied this technique to help further understand coronary artery blood flow in patients with unobstructed coronary arteries and to explore the detrimental effects of left ventricular hypertrophy. More recently, he has studied coronary blood flow in patients with regional left ventricular wall motion abnormalities.

In the aorta he has used the technique to describe an ‘horizon effect’, whereby waves reflections are attenuated from distant reflection sites. Currently, he is applying a new waves-reservoir model to separate the pressure waveform into its constituent waves and reservoir (windkessel) components. This technique helps explain why the blood pressure waveform undergoes such dramatic changes during ageing and disease.





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