2016 Biochemical Society Awards announced! Eleven distinguished scientists and exceptional early career researchers have been honoured in the Biochemical Society's annual Awards. The Awards recognize scientists for the excellence of their work, the profound impact their research has had and also highlight outstanding work by early career researchers. Find out more on the Biochemical Society website.

Latest Collection

microRNAs in health & disease: A collection of research papers and commissioned reviews on all aspects of microRNAs in indications ranging from non-small cell lung cancer, gastrointestinal cancer, cardiovascular disease, diabetic complications, skeletal muscle, kidneys, and stroke!

New Call For Papers

We invite the submission of original papers to one of the following Calls for Papers by the deadline of 30 November 2015:

  1. Post-translational modifications of proteins: clinical implications
  2. Mitochondria: biology and pathology
  3. Obesity and co-morbidities

Meeting Highlights

FEBS 2015: The Biochemical Basis of Life (July 4-9 2015)
FEBS 2015, the 40th FEBS Congress, will explore "The Biochemical Basis of Life". Topics covered include mechanisms of gene expression; membranes, receptors & bioenergetics; molecular neuroscience; and from chemical biology to molecular medicine.
More information available from the Biochemical Society website here.

Carbohydrate Active Enzymes in Medicine and Biotechnology (19-21st August 2015)
Carbohydrate active enzymes are ubiquitous in all kingdoms of life and vital in an abundance of cellular processes, including structural integrity, cell-cell/cell-pathogen interactions and protein folding. Topics include insights into carbohydrate active enzymes in medicine, and more information can be found here.

SPOTLIGHT

Eleonora Franzè, Ivan Monteleone, Maria Laura Cupi, Pamela Mancia, Flavio Caprioli, Irene Marafini, Alfredo Colantoni, Angela Ortenzi, Federica Laudisi, Giuseppe Sica, PierPaolo Sileri, Francesco Pallone and Giovanni Monteleone

IBD (inflammatory bowel disease)-related tissue damage occurs in areas which are massively infiltrated with monocytes/macrophages. These cells respond to inflammatory stimuli with enhanced production of cytokines/chemokines.
In this study from the latest issue of Clinical Science, Eleonora Franzè and colleagues analysed the expression and role of interleukin-34, a cytokine produced by many cell types, is highly synthesized in inflamed gut of patients with Crohn's disease and patients with ulcerative colitis, the two major IBD in human beings. In IBD, neutralization of IL-34 function attenuates mucosal production of inflammatory cytokines, and therefore IL-34 could be a promising target for therapeutic intervention in patients with these disorders.