2014 Impact Factor up to 5.629 - Clinical Science has received its highest ever Impact Factor of 5.629 in the 2013 Journal Citation Reports (Thomson Reuters 2014). A Top Quartile Journal in the Medicine (Research & Experimental) category, Clinical Science is now ranked 14 out of 122.

Latest Collection

Portland Press microRNA Collection, highlighting a selection of recent high-quality papers concerning various aspects in the field of miRNA that have been published in our family of journals (Biochemical Journal, Biochemical Society Transactions, Bioscience Reports and Clinical Science).

New Call For Papers

NADPH Oxidases in Health and Disease - we invite the submission of original papers by the deadline of 31 December 2014

Meeting Highlight

BSCR Autumn Meeting - Cardiovascular Signalling in Health and Disease, 8-9 September 2014, Reading, U.K. >> Meeting website


Kirsten Lindner, Joerg Haier, Zhe Wang, David I. Watson, Damian J. Hussey and Richard Hummel (University of Muenster, Muenster, Germany)

Identifying non-invasive biomarkers for the detection of cancer is an area of intense research. Circulating microRNAs are highly promising candidates in this context, as they present some key characteristics for cancer biomarkers. This Clinical Science Review highlights the origin of circulating microRNAs, their stability in blood samples and techniques to isolate exosomal microRNAs, and then addresses the current evidence supporting potential clinical applications of circulating miRNAs for diagnostic and prognostic purposes in the context of cancers of the gastrointestinal tract.