News

Congratulations to Susan Morton (Australian National University): winner of the Young Investigator Award sponsored by Clinical Science at State of the Heart 2014, held in Adelaide, Australia.

Latest Collection

Novel Models of Lung Disease: a Collection highlighting recent research papers and commissioned reviews on a range of animal models of lung disease.

New Call For Papers

We invite the submission of original papers to one of the following Calls for Papers by the deadline of 30 November 2015:

  1. Post-translational modifications of proteins: clinical implications
  2. Mitochondria: biology and pathology
  3. Obesity and co-morbidities

Meeting Highlights

Metabolic Drivers of Immunity
Obesity and nutrient excess are associated with inflammatory phenotypes and immune dysfunction. This joint Biochemical Society/British Society for Immunology conference will bring together key players to present emerging research on the importance of metabolism to normal maturation and differentiation of immune cells.
More information available from the Biochemical Society website here.

Experimental Biology 2015
(28 March to 1 April 2015): come and visit the Biochemical Society booth (#515) and find out more about publishing in Clinical Science.

SPOTLIGHT

Francesco P. Schena, Fabio Sallustio and Grazia Serino

miRNAs are packed within exosomes and released by cells for cellular communications; they are present in bodily fluids. Their study opens the way for understanding the pathogenetic mechanisms of many diseases; furthermore, as potential candidate biomarkers, they can be measured in bodily fluids for non-invasive monitoring of disease outcomes.
This review highlights recent advances in the role of miRNAs in the pathogenesis of primary and secondary glomerulonephritides such as IgA nephropathy, focal segmental glomerular sclerosis, lupus nephritis and diabetic nephropathy. The identification of reciprocal expression of miRNAs and their target genes provides the molecular basis for additional information on the pathogenetic mechanisms of kidney diseases. Recent findings demonstrate that miRNAs can be considered as potential targets for novel drugs.
podcast
Open access option available via Opt2Pay

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