Congratulations to Susan Morton (Australian National University): winner of the Young Investigator Award sponsored by Clinical Science at State of the Heart 2014, held in Adelaide, Australia.

Latest Collection

Novel Models of Lung Disease: a Collection highlighting recent research papers and commissioned reviews on a range of animal models of lung disease.

New Call For Papers

We invite the submission of original papers to one of the following Calls for Papers by the deadline of 30 November 2015:

  1. Post-translational modifications of proteins: clinical implications
  2. Mitochondria: biology and pathology
  3. Obesity and co-morbidities

Meeting Highlights

Metabolic Drivers of Immunity
Obesity and nutrient excess are associated with inflammatory phenotypes and immune dysfunction. This joint Biochemical Society/British Society for Immunology conference will bring together key players to present emerging research on the importance of metabolism to normal maturation and differentiation of immune cells.
More information available from the Biochemical Society website here.

Experimental Biology 2015
(28 March to 1 April 2015): come and visit the Biochemical Society booth (#515) and find out more about publishing in Clinical Science.


B. Feng, K. Zhang, R. Wang and L. Chen

Lung cancer is the leading cause of cancer-related death worldwide, with approximately 80-85% of cases being non-small-cell lung cancer (NSCLC). The miRNAs are small non-coding RNAs that regulate gene expression at a post-transcriptional level by either degradation or inhibition of the translation of target genes.
In their review, Chen and colleagues briefly describe the mechanisms of miRNA dysregulation in cancer as well as the oncogenic and tumour-suppressor functions of miRNAs in NSCLC. miRNAs could potentially be used as diagnostic or prognostic biomarkers of NSCLC, and the authors also explore miRNAs as new targets for NSCLC therapy.