News

2014 Impact Factor up to 5.629 - Clinical Science has received its highest ever Impact Factor of 5.629 in the 2013 Journal Citation Reports (Thomson Reuters 2014). A Top Quartile Journal in the Medicine (Research & Experimental) category, Clinical Science is now ranked 14 out of 122.

Latest Collection

Portland Press Mitochondria Collection, highlighting a selection of recent high-quality papers concerning various aspects in the field of mitochondrial biology that have been published in our family of journals (Biochemical Journal, Biochemical Society Transactions, Bioscience Reports and Clinical Science).

New Call For Papers

NADPH Oxidases in Health and Disease - we invite the submission of original papers by the deadline of 31 December 2014

Meeting Highlight

Congratulations to Dr Francisco Rios (University of Glasgow): winner of our Young Investigator Award at the recent HBPR2014 Scientific Sessions

SPOTLIGHT

Satoshi Kubota and Masaharu Takigawa (Okayama University Dental School, Okayama, Japan)

CCN family protein 2 (CCN2), also widely known as connective tissue growth factor (CTGF), is one of the founding members of the CCN family of matricellular proteins. Extensive investigation on CCN2 over recent years has revealed the novel molecular action and functional properties of this unique signalling modulator, and also its effects in development and disease. In this Review Article, the physiological and pathological roles of this unique protein are comprehensively summarized from a molecular network-based viewpoint of CCN2 functionalities.