Most Read papers

The most frequently downloaded papers for the 12 months to the end of February 2010 are shown below

7507	Review Molecular biology of human papillomavirus infection and cervical cancer John Doorbar (2006) 110, 525-541 doi:10.1042/CS20050369 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
4425	Review The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions Hiroyuki Takahashi and Masabumi Shibuya (2005) 109, 227-241 doi:10.1042/CS20040370 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
3993	Review Targeting vessels to treat hepatocellular carcinoma Pamela Romanque, Anne-Christine Piguet and Jean-François Dufour (2008) 114, 467-477 doi:10.1042/CS20070310 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
3747	Review Diabetic cardiomyopathy: mechanisms, diagnosis and treatment Sajad A Hayat, Billal Patel, Rajdeep S Khattar and Rayaz A Malik (2004) 107, 539-557 doi:10.1042/CS20040057 Abstract | Legacy HTML | Full text PDF
3601	Review Urinary microalbumin/creatinine ratios: reference range in uncomplicated pregnancy Jason Waugh, Stephen C Bell, Mark D Kilby, Paul C Lambert, Claire N Blackwell, Andrew Shennan and Aidan Halligan (2003) 104, 103-107 doi:10.1042/CS20020170 Abstract | Legacy HTML | Full text PDF
3533	Review The Role of TNFa in Vascular Dysfunction Hanrui Zhang, Yoonjung Park, junxi Wu, Xiuping Chen, Sewon Lee, Jiyeon Yang, Kevin Dellsperger and Cuihua Zhang (2009) 116, 219-230 doi:10.1042/CS20080196 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
3333	Clinical and therapeutic significance of the Na+,K+ pump* T Clausen (1998) 95, 3-17 Abstract | Legacy HTML | Full text PDF
3288	Review Hepatocellular transport in acquired cholestasis: new insights into functional, regulatory and therapeutic aspects Marcelo Roma, Fernando Crocenzi and Enrique Sánchez Pozzi (2008) 114, 567-588 doi:10.1042/CS20070227 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
3251	Review Cellular and Molecular Biology of HCV Infection and Hepatitis Hengli Tang and Henry Grise (2009) 117, 49-65 doi:10.1042/CS20080631 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
3194	Review Diabetic Cardiomyopathy Omar Asghar, Ahmed Al-sunni, Kaivan Khavandi, Ali Khavandi, Sarah Withers, Adam Greenstein, Anthony Heagerty and Rayaz Malik (2009) 116, 741-760 doi:10.1042/CS20080500 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
3188	Review Sensitivity of bone to glucocorticoids Mark S Cooper (2004) 107, 111-123 doi:10.1042/CS20040070 Abstract | Legacy HTML | Full text PDF
2986	Review Role of nitric oxide in the regulation of cardiovascular autonomic control S Chowdhary and J N Townend (1999) 97, 5-17 Abstract | Legacy HTML | Full text PDF
2892	Review Non-alcoholic Fatty Liver Disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations David Preiss and Naveed Sattar (2008) 115, 141-150 doi:10.1042/CS20070402 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2800	Review Vascular complications in diabetes mellitus: the role of endothelial dysfunction Casper G Schalkwijk and Coen D A Stehouwer (2005) 109, 143-159 doi:10.1042/CS20050025 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2716	Editorial Anti-inflammatory actions of glucocorticoids: molecular mechanisms P J Barnes (1998) 94, 557-572 Abstract
2633	Review Statins and their role in vascular protection Justin C Mason (2003) 105, 251-266 doi:10.1042/CS20030148 Abstract | Legacy HTML | Full text PDF
2612	Review The role of adiponectin and visfatin as regulators of inflammation: involvement in obesity-associated diseases Herbert Tilg and Alexander Moschen (2008) 114, 275-288 doi:10.1042/CS20070196 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2300	Review MicroRNAs: Role in Cardiovascular Biology and Disease Chunxiang Zhang (2008) 114, 699-706 doi:10.1042/CS20070211 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2274	Review Clinical relevance of the neurotrophins and their receptors Shelley J Allen and David Dawbarn (2006) 110, 175-191 doi:10.1042/CS20050161 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2187	Review Mechanisms by which fatty acids regulate leukocyte function Thais Lima, Renata Gorjão, Elaine Hatanaka, Maria Fernanda Cury-Boaventura, érica Silva, Joaquim Procópio and Rui Curi (2007) 113, 65-77 doi:10.1042/CS20070006 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2153	Review RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights Liming Jin and Arthur L Burnett (2006) 110, 153-165 doi:10.1042/CS20050255 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
2153	Review Pathophysiology of acute lung injury in combined burn and smoke inhalation injury Perenlei Enkhbaatar and Daniel L Traber (2004) 107, 137-143 doi:10.1042/CS20040135 Abstract | Legacy HTML | Full text PDF
2086	In utero programming of chronic disease D J Barker (1998) 95, 115-128 Abstract | Legacy HTML | Full text PDF
2017	Review AMP-activated Protein Kinase Pathway:A Potential Therapeutic Target in Cardiometabolic Disease Aaron Wong, Jacqueline Howie, John Petrie and Chim Lang (2009) 116, 607-620 doi:10.1042/CS20080066 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1948	Review Short interfering RNA (siRNA): tool or therapeutic? Daniel Cejka, Doris Losert and Volker Wacheck (2006) 110, 47-58 doi:10.1042/CS20050162 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1946	Review Mitochondrial DNA and aging Mikhail F Alexeyev, Susan P Ledoux and Glenn L Wilson (2004) 107, 355-364 doi:10.1042/CS20040148 Abstract | Legacy HTML | Full text PDF
1913	Review Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches Thomas Jansson and Theresa Powell (2007) 113, 1-13 doi:10.1042/CS20060339 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1877	Review Real-time reverse transcription PCR (qRT-PCR) and its potential use in clinical diagnosis Stephen A Bustin and Reinhold Mueller (2005) 109, 365-379 doi:10.1042/CS20050086 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1862	Review Neurotrophin signalling in health and disease Moses V Chao, Rithwick Rajagopal and Francis S Lee (2006) 110, 167-173 doi:10.1042/CS20050163 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1861	Review Bioactive natural compounds for the treatment of gastrointestinal disorders Subrata Ghosh and Raymond J Playford (2003) 104, 547-556 doi:10.1042/CS20030067 Abstract | Legacy HTML | Full text PDF
1841	Review New insights into the relationship between airway inflammation and asthma A J Wardlaw, C E Brightling, R Green, G Woltmann, P Bradding and I D Pavord (2002) 103, 201-211 doi:10.1042/ Abstract | Legacy HTML | Full text PDF
1830	Review Signal transduction in prostate cancer progression Daniel Gioeli (2005) 108, 293-308 doi:10.1042/CS20040329 Abstract | Legacy HTML | Full text PDF
1826	Review Angiotensin II signal transduction through the AT{sub1} receptor: novel insights into mechanisms and pathophysiology Sadaharu Higuchi, Haruhiko Ohtsu, Hiroyuki Suzuki, Heigoro Shirai, Gerald Frank and Satoru Eguchi (2007) 112, 417-428 doi:10.1042/CS20060342 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1817	Review S-Nitrosothiols: a class of nitric oxide-donor drugs H Al-Sa'doni and A Ferro (2000) 98, 507-520 Abstract | Legacy HTML | Full text PDF
1810	Review Visfatin/PBEF/Nampt: structure, regulation, and potential function of a novel adipokine Grit Sommer, Antje Garten, Stefanie Petzold, Annette Beck-Sickinger, Matthias Blüher, Michael Stumvoll and Mathias Fasshauer (2008) 115, 13-23 doi:10.1042/CS20070226 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1785	Review Eicosanoids and renal vascular function in diseases John D Imig (2006) 111, 21-34 doi:10.1042/CS20050251 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1774	Effects of creatine loading and prolonged creatine supplementation on body composition, fuel selection, sprint and endurance performance in humans Luc J C van Loon, Audrey M Oosterlaar, Fred Hartgens, Matthijs K C Hesselink, Rodney J Snow and Anton J M Wagenmakers (2003) 104, 153-162 doi:10.1042/CS20020159 Abstract | Legacy HTML | Full text PDF
1769	Review Strategies to reduce oxidative stress in cardiovascular disease Carlene A Hamilton, William H Miller, Sammy Al-Benna, M Julia Brosnan, Russell D Drummond, Martin W McBride and Anna F Dominiczak (2004) 106, 219-234 doi:10.1042/CS20030379 Abstract | Legacy HTML | Full text PDF
1724	The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56) R J Stevens, V Kothari, A I Adler and I M Stratton and (2001) 101, 671-679 Abstract | Legacy HTML | Full text PDF
1694	Review Molecular mechanisms controlling the coupled development of myocardium and coronary vasculature Shoumo Bhattacharya, Simon MacDonald and Cassandra Farthing (2006) 111, 35-46 doi:10.1042/CS20060003 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1688	Review Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders Mark D Gorrell (2005) 108, 277-292 doi:10.1042/CS20040302 Abstract | Legacy HTML | Full text PDF
1636	Review MAPK Signaling in Cardiovascular Health and Disease: Molecular Mechanisms and Therapeutic Targets Anthony Muslin (2008) 115, 203-218 doi:10.1042/CS20070430 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1606	Review NADPH oxidase and endothelial cell function Robin Ray and Ajay M Shah (2005) 109, 217-226 doi:10.1042/CS20050067 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1601	Review Alpha(2)-adrenergic receptor signalling in hypertension Nancy L Kanagy (2005) 109, 431-437 doi:10.1042/CS20050101 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1569	Review Modulation of the natriuretic peptide system in heart failure: from bench to bedside? Matthias Schmitt, John R Cockcroft and Michael P Frenneaux (2003) 105, 141-160 doi:10.1042/CS20030044 Abstract | Legacy HTML | Full text PDF
1563	Commentary Increased plasma urotensin II levels in patients with diabetes mellitus Kazuhito Totsune, Kazuhiro Takahashi, Zenei Arihara, Masahiko Sone, Sadayoshi Ito and Osamu Murakami (2003) 104, 1-5 doi:10.1042/ Abstract | Legacy HTML | Full text PDF
1549	Review Molecular genetics of human hypertension Maolian Gong and Norbert Hubner (2006) 110, 315-326 doi:10.1042/CS20050208 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF
1539	Review Angiotensin receptors: distribution, signalling and function D T Dinh, A G Frauman, C I Johnston and M E Fabiani (2001) 100, 481-492 Abstract | Legacy HTML | Full text PDF
1520	Review Sex steroids and insulin resistance Callum Livingstone and Mary Collison (2002) 102, 151-166 Abstract | Legacy HTML | Full text PDF
1487	Review Mechanisms underlying the role of glucocorticoids in the early life programming of adult disease Amanda Drake, Justin Tang and Moffat Nyirenda (2007) 113, 219-232 doi:10.1042/CS20070107 Abstract | Enhanced Full Text | Legacy HTML | Full text PDF