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Does activation of the FcγRIIa play a role in the pathogenesis of the ALI/ARDS?

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are inflammatory diseases of the lung, and lung fluids from patients with ALI/ARDS contain plasma proteins and inflammatory mediators, including immunoglobulins. In this article, Anna Kurdowska and colleagues put forward a hypothesis suggesting that Fcγ receptors (receptors interacting with the Fc portion of IgG) may contribute to the disease process of ALI/ARDS

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