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Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications

Atherosclerosis is the pathological process that underlies the development of cardiovascular disease, and is driven by the recruitment of inflammatory cells into the artery wall. In the present review, David Greaves and colleagues discuss the murine models of atherosclerosis that have been used to give insights into the cellular and molecular mechanisms regulating inflammatory cell recruitment, and potential novel therapeutic avenues for the treatment of cardiovascular disease.

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